After reconstituting Melanotan 2 MT-2 should be refrigerated at temperatures not to exceed 36 F. This product is NOT for human use and can be harmful if ingested. This product should only be handled by licensed, qualified professionals. If you buy peptides online from us, they are not peptides for bodybuilding. Source: PubChem. Melanotan 2 produces its effects by binding with melanocortin receptors.
There are five known melanocortin receptors, each with different function. The newest research finding for MT-2 indicates that the peptide can reverse certain autistic features in a commonly used mouse model of autism spectrum disorder ASD. There is no treatment for the condition, but recent search has indicated that oxytocin therapy may be useful in mitigating some of the behavioral problems associated with ASD.
Using a mouse model of maternal immune activation known to lead to autism, researchers investigated whether MT2, which is known to stimulate oxytocin release, could counteract ASD or reduce common ASD behviors. Their research revealed that administration of MT-2 reverses the decreased communication, impaired social interaction, and repetitive behaviors associated with autism in this particular model. In fact, the researchers found that MT-2 administration increased the expression of oxytocin receptors in specific parts of the brain, suggesting a direct correlation between oxytocin signaling in those areas and ASD-specific behaviors [ 1 ].
Source: PubMed. These findings not only suggest potential avenues for developing a treatment for ASD, they have helped to define a specific brain pathway that may be integral to the development of ASD in the first place. These findings could help scientists develop a complete model of ASD and thus both treatments and preventative measures. There is good evidence to suggest that MT-2 can reduce fat storage and hunger behavior in animal models. Administration of MT-2 to mice causes significant reductions in how much food they consume, but also changes their preference for fatty foods.
Mice given MT-2 ignore fatty foods, which they would otherwise prefer. Similarly, mice devoid of the MC-4R receptor consume fatty foods almost exclusively and are immune to the effects of MT-2 [ 2 ]. The effects of MT-2 are similar to those of the hormone leptin, sometimes called the satiety hormone because it reduces cravings and food intake.
Leptin, however, has never been useful in the treatment of obesity, even in individuals who are leptin deficient. This is likely because there are two pathways for satiety, called leptin-dependent and leptin-independent pathways. Research suggests MT-2 is more effective in stimulating both pathways and thus may be a more effective exogenous treatment for reducing hunger [ 3 ], [ 4 ].
This latter finding has been bolstered by the discovery that thyrotropin-releasing hormone TRH gene expression, which has long been known to play a role in the leptin-satiety pathway, is also affected by MC-4R stimulation [ 5 ]. Both MT-2 and leptin are thought to cause an increase in TRH expression in the paraventricular nucleus of the hypothalamus, a region of the brain associated with satiety and food intake, but only MT-2 crosses into the central nervous system in concentrations high enough to have an effect on TRH expression.
The pathogenesis of diabetes is defined by high blood sugar levels, hypersecretion of glucagon, and the production of ketone bodies [ 6 ].
It has been known for some time that leptin counteracts these factors by increasing the uptake of glucose, suppressing glucagon production, and interfering with the pathway that leads to ketone body formation.
These actions do not depend on insulin and thus leptin signaling is being actively investigated as an alternative means by which diabetes might be treated. What it does is to limit damage to the skin by the production of melanin and the protection of deep skin pigmentation in the form of a tan. Once peptides have been reconstituted, they must be kept refrigerated.
For this reason, like all our peptides Melanotan 2 Norway is sold in the form of lyophilized powder. Before being used, it must be mixed with bacteriostatic water. This keeps the peptide fresh for longer and prevents bacteria from developing. After reconstitution, it must be stored in the fridge. However we understand that not everyone would prefer to use tanning injections, and that is why we have developed our Melanotan nasal sprays!
They are incredibly non-invasive, convenient and easy to use! Shopping for peptides has never been made easier! We also sell Melanotan 2 and PT in a nasal spray form.
We put our customers first!
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